Sunday, March 12, 2023

Adenylcyclase


Adenylyl cyclase (AC) is an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) into cyclic adenosine monophosphate (cAMP). This enzyme is involved in the regulation of many physiological processes, including metabolism, muscle contraction, neurotransmission, and hormone synthesis.

AC is present in many different types of cells, including neurons, muscle cells, and endocrine cells. It is activated by a variety of signals, including neurotransmitters, hormones, and calcium ions. Once activated, AC generates cAMP, which then activates downstream signaling pathways that ultimately lead to cellular responses.

The regulation of AC activity is complex and involves a variety of mechanisms, including receptor-mediated activation and inhibition by other intracellular signaling pathways. AC dysfunction has been implicated in a number of diseases, including obesity, diabetes, and cancer, and the development of AC inhibitors is an area of active research for the treatment of these diseases.


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